王雪莹简历
王雪莹,济南大学,化学化工学院,讲师,硕士生导师,校聘A3岗。
教育经历
2010/09 - 2014/12,武汉大学,分析化学,博士,
2007/09 - 2010/06,济南大学,分析化学,硕士,
2003/09 - 2007/06, 济南大学,应用化学,学士,
科研与学术工作经历
2017/10-现在,济南大学,化学化工学院,讲师
2015/01-2017/09,山东省科学院,能源研究所,助理研究员
主持或参加科研项目(课题)及人才计划项目情况
(1)国家自然科学青年科学基金,21605094,体外水凝胶肝血管模型构建及其用于载药微球释药行为研究,2017/01-2019/12,20万,主持
(2)山东省科学院青年基金,基于三维血管网络的体外药物评价模型模拟研究,2017/01-2018/12,15万,主持。
(3)山东省三院联合基金项目,ZR2015YL006, 体外研究病理条件下流体剪切力对药物释放的影响,2015/07-2017/12,10万元,主持。
主要研究方向
作为项目负责人主持科研项目多项,发表多篇SCI论文。主要科研方向为微流控芯片构建。主要利用微流控技术体外模拟人造血管,并构建三维的血管微环境,研究肿瘤药物的性质等。同时,利用微流控技术制备高性能的纳米材料并用于肿瘤标志物的灵敏检测。
近年代表性研究成果和学术奖励情况
1. Yuanling Sun, Xueying Wang*, Han Xu, Chaofan Ding, Yanna Lin, Chuannan Luo**, Qin Wei. Achemiluminescence aptasensor for thrombin detection based on aptamer-conjugated and hemin/G-quadruplex DNAzyme signalamplified carbon fiber composite. Analytica Chimica Acta, 2018, 1043: 132-141. (IF=5.256)
2. Chaofan Ding, Xueying Wang, Hao Liu, Yue Li, Yuanling Sun,Yanna Lin, Weiyan Sun, Xiaodong Zhu, Yuxue Dai, Chuannan Luo*. Glyphosate removal from water by functional three-dimensional graphene aerogels. Environmental Chemistry, 2018, 15, 325-335. (IF=2.193)
3. Yanna Lin, Xueying Wang*, Yuanling Sun, Yuxue Dai, Weiyan Sun, Xiaodong Zhu, Hao Liu, Rui Han, Dandan Gao, Chuannan Luo**. A chemiluminescent biosensor for ultrasensitive detection of adenosine based on target-responsive DNA hydrogel with Au@HKUST-1 encapsulation. Sensors and Actuators B: Chemical, 2019, 289: 56-64. (IF=6.303)
4. Yuanling Sun, Yanna Lin, Rui Han, Xueying Wang*, Chuannan Luo**. A chemiluminescence biosensor for lysozyme detection based on aptamers and hemin/G-quadruplex DNAzyme modifed sandwich-rod carbon fber composite. Talanta, 2019, 200: 57-66. (IF=4.916)
5. Yanna Lin, Yuanling Sun, Yuxue Dai, Weiyan Sun, Xiaodong Zhu, Hao Liu, Rui Han, Dandan Gao, Chuannan Luo*, Xueying Wang**. A “signal-on” chemiluminescence biosensor for thrombin detection based on DNA functionalized magnetic sodium alginate hydrogel and metalloporphyrinic metal-organic framework nanosheets. Talanta, 2020, 207: 120300. (IF=4.916)
6. Yuanling Sun, YannaLin Weiyan Sun, Rui Han, Chuannan Luo∗, Xueying Wang∗∗, Qin Wei. A highly selective and sensitive detection of insulin with chemiluminescence biosensor based on aptamer and oligonucleotide-AuNPs functionalized nanosilica @ graphene oxide aerogel. Analytica Chimica Acta, 2019, 1089: 152-164. (IF=5.256)
7. Hao Liu, Xueying Wang, Chaofan Ding, Yuxue Dai, Yuanling Sun,Yanna Lin, Weiyan Sun, Xiaodong Zhu, Rui Han, Dandan Gao, Chuannan Luo∗. Carboxylated carbon nanotubes-graphene oxide aerogels as ultralight and renewable high performance adsorbents for efficient adsorption of glyphosate. Environmental Chemistry, 2019, DOI: 10.1071/EN19107. (IF=2.193)
8. Yuanling Sun, Rui Han, Yuxue Dai, Xiaodong Zhu, Hao Liu, Dandan Gao, Chuannan Luo∗, Xueying Wang∗∗, Qin Wei. Highly selective and sensitive streptomycin chemiluminescence sensor based on aptamer and G-quadruplex DNAzyme modified three-dimensional graphene composite. Sensors and Actuators B: Chemical, 2019, 301: 127122. (IF=6.303)
9. Xiaodong Zhu, Yuxue Dai, Yuanling Sun, Hao Liu, Weiyan Sun, Yanna Lin, Dandan Gao, Rui Han, Xueying Wang∗∗, Chuannan Luo∗. Rapid fabrication of electrode for the detection of alpha fetoprotein based on MnO2 functionalized mesoporous carbon hollow sphere. Materials Science & Engineering C, 2020, 107: 110206. (IF=4.959)
10. Xiaodong Zhu, Hao Liu, Yuxue Dai, Xueying Wang, Chuannan Luo*, Qin Wei. Enhanced electrochemiluminescence of luminol based on Cu2O–Au heterostructure enabled multiple-amplifcation strategy. Biosensors and Bioelectronics, 2020, 111970. (IF=9.518)
11. Yuanling Sun, Yuxue Da, Xiaodong Zhu, Rui Han, Xueying Wang∗, Chuannan Luo∗∗. A nanocomposite prepared from bifunctionalized ionic liquid, chitosan, graphene oxide and magnetic nanoparticles for aptamer-based assay of tetracycline by chemiluminescence. Microchimica Acta, 2020, 187: 63. (IF=5.479)
12. Xue-Ying Wang#,Ying-Pei#,Min-Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-HuaHuang*,An artificial blood vessel implanted three-dimensional microsystem for modeling transvascularmigration of tumor cells,Lab Chip,2015,15(4):1178-1187.
13. Liu Yan-Ling#,Wang Xue-Ying, Xu Jia-Quan, XiaoChong,LiuYan-Hong, Zhang Xin-Wei, Liu Jun-Tao ,Huang Wei-Hua*, Functionalized graphene-based biomimetic microsensor interfacing with living cells to sensitively monitor nitric oxide release, Chem. Sci.,2015,6 (3): 1853-1858.
14. Li Yu-Tao#,Zhang Shu-Hui#, Wang Xue-Ying,Zhang Xin-Wei,Oleinick Alexander I,Svir Irina,Amatore Christian,Huang Wei-Hua*, Real-time Monitoring of Discrete Synaptic Release Events and Excitatory Potentials with in Self-reconstructed Neuromuscular Junctions.,Angew Chem Int Ed Engl,2015,54(32):9313-9318.
15. Xue-Ying Wang#,Zi-He Jin#,Bo-Wen Gan,Song-Wei Lv,Min Xie,Wei-Hua Huang*,Engineering interconnected 3D vascular networks in hydrogels using molded sodium alginate lattice as the sacrificialtemplate,Lab chip,2014,14(15):2709-2716.
16.Ying Pei#,Xue-Ying Wang#,Weihua Huang,Pan Liu,Lina Zhang*,Cellulosse-based hydrogels withexcellent microstructural replication ability and cytocompatibility for microfluidic devices,Cellulose,2013,20(4):1897-1909.
17. Lin-Mei Li#,Xue-Ying Wang#,Liang-Sheng Hu,Rong-Sheng Chen,Ying Huang,Shi-Jin Chen,Wei-HuaHuang*,Kai-Fu Huo*,Paul K.Chu,Vascular lumen simulation and highly-sensitive nitric oxidedetection using three-dimensional gelatin chip coupled to TiC/C nanowire arrays microelectrode,Labchip,2012,12(21):4249-4256.
18. Xueying Wang#,Chuannan Luo*,Zhen Lv,Fuguang Lu,Investigation of the inclusion behavior betweenp-sulfoniccalix[8]arene and norfloxacin by fluorescence spectroscopy,Journal ofLuminescence,2011,131(9):1986-1990.