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姓名 于京华
学历/学位研究生/博士
职称/职务教授, 博士生导师
联系电话0531-82767161
电子邮箱chm_yujh@ujn.edu.cn
实验室/办公室逸夫科学楼B528
主讲课程分析化学、工业分析
科研方向:1. 食品安全的检验与控制
利用化学传感器与光电分析相结合,实现对食品中有害成分的特效识别、快速简便、多组分的在线同时检测,为食品安全问题提供可靠的检测手段。
2. 新型仿生传感器的构建及应用
研究开发新型功能化材料仿生传感器,具有性能好、寿命长、耐酸耐碱、耐高温等特点。可应用于实际样品农药残留检测和药物控释。
3. 化学传感器的开发及利用
致力于高灵敏度、痕量物质的分析方法的建立,开发具有各种功能的新型化学传感器,实现现场即时食品与环境样品多组分同时监测。
4. 微流控纸芯片的设计开发
在纸芯片上新型功能纳米材料构建生物传感器,实现对生命物质的快速、方便的检测。
科研成果及奖励(包括项目、专利、鉴定等)(2005年以来):
主要从事新型仿生传感器的构建及应用、新型免疫分析技术的研究、食品安全的检验与控制。先后主持和参加了多项国家自然科学基金、国家十一五科技支撑计划子课题、国家“863”计划、“973”项目子课题等多项国家级和省级项目。参加的研究课题先后获得国家技术发明二等奖1项,山东省技术发明一等奖1项,省科技进步一等奖1项,省部级科技进步二等、三等奖3项,第一发明人发明专利10项。
主持项目:
1.基于微流控纸芯片的持久性有机氯农药残留光致电化学检测-国家自然科学基金-(21277058)
2.基于纸芯片实验室的电致化学发光免疫分析研究-国家自然科学基金-(21175058)
3.基于分子自组装微球的自修复水泥材料的研究-国家自然科学基金-(50972050)
4.农药残留现场检测微流控纸芯片的应用基础研究-山东省自然科学基金点项目-(ZR2012BZ002)
5.高通量电致化学发光多元免疫分析系统的开发及其应用-山东省科技发展计划-(2011GGB01153)
6.新型试剂的合成及流动注射化学发光法在药物分析中的应用-山东省自然科学基金-(Y2007B07)
教学成果与奖励(2005年以来):1. 2011年山东省研究生优秀科技创新成果一等奖“高选择性发光分析检测池器件的设计制作”,指导教师
2. 2012年山东省研究生优秀硕士论文"基于功能材料的分子识别发光传感器的研究与应用",指导教师
3. 2013年山东省研究生优秀科技创新成果一等奖“基于电池的纸上电化学发光传感器件的设计制作”,指导教师
4. 2013年第十三届“挑战杯"全国大学生课外学术科技作品竞赛,一等奖,指导教师
5. 2014年全国首批大学生"小平科技创新团队"指导教师
6. 2014年山东省研究生优秀科技创新成果一等奖“低成本、高通量生物传感器件设计制作”,指导教师
代表性论文(2005年以来):以第一作者或通讯作者发表论文:
1.Molecularly imprinted polymer grafted porous Au-paperelectrode for an microfluidic electro-analytical origamidevice, Advanced Functional Materials,23(24), 3115-3123, 2013.(IF=9.765)
2.Electrogenerated chemiluminescence from aphenyleneethynylene derivative and its ultrasensitiveimmunosensing application using a nanotubularmesoporous Pt-Ag alloy for signal amplification, Advanced Functional Materials,22(18), 3899-3906, 2012. (IF=9.765, 封面文章)
3.Photoelectrochemical lab-on-paper device based on anintegratedpaper supercapacitor and internal light source, AnalyticalChemistry,85(8), 3961-3970, 2013. (IF=5.695)
4.Three-dimensionalpaper-based electrochemiluminescence immunodevice for multiplexed measurement of biomarkers andpoint-of-care testing, Biomaterials, 33(4), 1024-1031, 2012. (IF=7.604)
5.Electrochemical immunoassay on a immunoassay on a3D microfluidic paper-based device, Chemical Communication, 48(39), 4683-4685, 2012.(IF=6.378, 封面文章)
6.A microfluidic origami electrochemiluminescenceaptamer-device based on a porous Au-paper electrodeand a phenyleneethynylene derivative, Chemical Communication,49(14), 1383-1385, 2013.(IF=6.378, 封面文章)
7.Rechargeable battery-triggered electrochemiluminescence detection onmicrofluidic origami immunodevice based on two electrodes, Chemical Communication,48(80), 9971-9973, 2012. (IF=6.378, 封面文章)
8.A paper-based photoelectrochemical immunoassay forlow-cost and multiplexed point-of-care testing, Chemical Communication,49(32), 3294-3296, 2013. (IF=6.378, 封面文章)
9.Paper-based photoelectrochemical immunosensingbased on CdS QD sensitized multidimensional porousZnO spheres promoted by carbon nanotubes, Chemical Communication,49(88), 10400-10402, 2013.(IF=6.378)
10.A 3D origami multiple electrochemiluminescenceimmunodevice based on a porous silver-paperelectrode and multi-labeled nanoporous gold–carbonspheres, Chemical Communication,49(70), 7687-7689. (IF=6.378, 封面文章)
11.Flexible paper-based ZnO nanorod light-emittingdiodes induced multiplexed photoelectrochemicalimmunoassay, Chemical Communication,50(12), 1417-1419, 2014. (IF=6.378, 封面文章)
12.A three-dimensional origami-basedimmuno-biofuel cell for self-powered,low-cost, and sensitive point-of-care testing, Chemical Communication,50(16), 1947-1949, 2014.(IF=6.378, 封面文章)
13.A novel conjugated Polyfluorene: synthesis, characterization and its application in label-freeECL immunoassay for biomarker detection,Journal of Materials Chemistry, 22(12), 5568-5573, 2012.(IF=6.101)
14.Synthesis and characterization of graphene nanosheetsattached to spiky MnO2nanospheres and its application inultrasensitive immunoassay,Carbon, 57, 22-33, 2013.(IF=5.868)
15.Paper-basedElectrochemiluminescence Three-dimensional Immunodevice forLab-on-paper, Specific and SensitivePoint-of-Care Testing,Chemistry -A European Journal, 18(16), 4938-4945, 2012. (IF=5.831)
16.Microfluidic Paper-BasedChemiluminescence Biosensor for Simultaneous Determination of Glucose and Uric Acid,Lab on a chip,11(7), 1286-1291, 2011. (IF=5.697, 封面文章)
17.3D Origami-based multifunction-integrated immunodevice: low-cost andmultiplexed sandwich chemiluminescence immunoassay on microfluidic paper-basedanalytical device,Lab on a chip,12(17), 3150-3158, 2012. (IF=5.697)
18.Battery-triggered microfluidic paper-based multiplexelectrochemiluminescence immunodevice based on potential-resolutionstrategy,Lab on a chip,12(21), 4489-4498, 2012. (IF=5.697)
19.Photoelectrochemical lab-on-paper device equippedwith a porous Au-paper electrode and fluidic delay-switchfor sensitive detection of DNA hybridization,Lab on a chip,13(19), 3945-3955, 2013. (IF=5.697)
20.A novel chemiluminescence papermicrofluidic biosensor based on enzymatic reaction for uric acid determination,Biosensors andBioelectronics, 26, 3284-3289, 2011. (IF=5.437)


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