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姓名 葛慎光
学历/学位研究生/博士
职称/职务副教授、校聘A5岗教授
联系电话0531-82767161
电子邮箱chm_gesg@ujn.edu.cn
实验室/办公室逸夫科学楼B-528
主讲课程分析化学、新型功能材料、分光光度分析
科研方向:

1.功能纳米材料制备、纳米与生物分子的相互作用

2.生物传感器的构建及应用、传感器信号转换与放大新原理和新方法

3.微流控纸芯片性能调控和传感机制研究、器件的开发和研制

4.电化学分析、光致电化学分析、比色分析、荧光分析及荧光成像

科研成果及奖励(包括项目、专利、鉴定等)(2005年以来):

 

主持项目

1.国家自然科学基金青年基金-基于点击化学的微囊藻毒素化学传感器构建-No.21207048)

2.国家自然科学基金面上项目-基于中空通道纸芯片的自推进分离捕获循环肿瘤细胞及原位分析-(No.21575051)

3.山东省自然科学基金-功能化石墨烯电化学传感器的构建及其在免疫学中应用-No.ZR2011BQ019

4.山东省自然科学基金/省属高校优秀青年基金-多功能纸芯片分离捕获外周血中肿瘤细胞及原位分析-(No.ZR2015JL006

5.山东省科技发展计划-研制纸芯片器件对水体中农药残留的检测与监控-No. 2014GGX103012

6.济南市青年科技明星计划-含反应基团的Si/C/N陶瓷前驱体聚硅氮烷的制备及性能研究-No.20110102

7.中国科学院环境化学与生态毒理学国家重点实验室开放基金-基于纸微芯片的电化学发光免疫分析研究-No.KF2011-03

8.济南大学博士基金-纸微芯片上电致化学发光行为研究-(No.XBS1428

 

发明专利:

1.检测痕量农药残留物的分子印迹化学发光传感器及其应用-(发明专利:ZL200910018139.8

2.检测痕量农药残留物的电致化学发光传感器的制备及应用-(发明专利:ZL 201010507594.7

3.水泥材料自修复的分子自组装微球制备及应用-(发明专利:ZL201010524199.X

4.一种基于点击化学仿生分子印迹电化学传感器的制备及对食品过敏原的检测-(发明专利:201210472177.2

5. 可寻址电化学传感器阵列的制备及用于多种肿瘤标志物的检测和癌症筛查,201210472349.6)

6. 具有叶酸受体靶向和荧光双功能金簇的制备方法-(发明专利:201410125041.3)

7. 用于叶酸过表达癌细胞快速检测的比色方法-(发明专利:201410124906.4)

教学成果与奖励(2005年以来):

科技奖励

1.纸芯片传感器纳米材料构建传感界面和实现信号放大,山东省高等学校优秀科研成果奖一等奖。

2.纸芯片传感器纳米材料构建传感界面和实现信号放大,济南大学优秀科研成果一等奖。

3.基于新型发光试剂和传感器设计的高选择性发光分析研究,山东省高等学校优秀科研成果奖一等奖。

4.新型荧光试剂的合成及在分析中应用,济南大学优秀科研成果二等奖。

5.新型荧光探针的设计及在环境检测中的研究,济南大学优秀科研成果三等奖。

6.含共轭结构的有机硅聚合物的制备及应用,山东省科技进步奖 三等奖。

7.新型多功能聚硅氮烷的开发及应用研究,中国石油和化学工业联合会 三等奖。

8.新型含氮聚硅烷的制备与应用,中国建筑材料联合会 科技进步二等奖。

9.微流控纸芯片的功能调控技术及其应用,中国石油与化学工业联合会 二等奖。

 

代表性论文(2005年以来): 

1. Shenguang Ge,  Weiping Li, Mei Yan, Xianrang Song and Jinghua Yu, Photoelectrochemical Detection of Tumor Marker Based on CdS Quantum Dots/ZnO Nanorods/Au@Pt-Paper Electrode 3D Origami Immunodevice, Jouranl of Materials Chemistry B, 2015, 3, 2426–2432.

2. Shenguang Ge, Weiyan Liu, Haiyun Liu, Fang Liu, Jinghua Yu, Mei Yan*, Jiadong Huang*Colorimetric detection of the flux of hydrogen peroxide released from living cells based on the high peroxidase-like catalytic performance of porous PtPd nanorods, Biosensors and Bioelectronics, 2015, 71, 456-462.

3. Long Li, Lina Zhang, Jinghua Yu, Shenguang Ge*, Xianrang Song*, All-Graphene Composite Materials for Signal Amplification toward Ultrasensitive Electrochemical Immunosensing of Tumor Marker, Biosensors and Bioelectronics, 2015, 71, 108-114.

4. Guoqiang Sun, Hongmei Yang, Yan Zhang, Jinghua Yu, Shenguang Ge*, Mei Yan, Xianrang Song, Branched zinc oxide nanorods arrays modified paper electrode for electrochemical immunosensing by combining biocatalytic precipitation reaction and competitive immunoassay mode, Biosensors and Bioelectronics, 2015, 74, 823–829.

5. Shenguang Ge, Yan Zhang, Lina Zhang, Linlin Liang, Mei Yan, Jiadong Huang, Jinghua Yu,* and Mingwei Sun,  Nanoparticles for Signal Amplification on Lab-on-Paper Device, Sensors and Actuators B, 2015, 220, 665-672.

6. Shenguang Ge, Lina Zhang, Jinghua Yu*, Paper-based microfluidic devices in bioanalysis: how far have we come? , Bioanalysis, 2015, 7(6), 633-636.

7. Shenguang Ge, Feifei Lan, Feng Yu, Jinghua Yu*, Applications of Graphene and Related Nanomaterials in Analytical Chemistry, New Journal of Chemistry, 2015, 39, 2380--2395.

8. Shenguang Ge, Fang Liu, Weiyan Liu, Mei Yan, Xianrang Song and JinghuaColorimetric assay of K-562 cells based on folic acid-conjugated porous bimetallic Pd@Au nanoparticles for point-of-care testingChem. Commun., 2014, 50, 475--477.

9. Shenguang Ge, Mingwei Sun, Weiyan Liu, Shuai Li, Xiu Wang, Chengchao Chu, Mei Yan, Jinghua Yu, Disposable electrochemical immunosensor based on peroxidase-like magnetic silica–graphene oxide composites for detection of cancer antigen 153, Sensors and Actuators B 2014, 192, 317– 326

10. Shenguang Ge, Lei Ge, Mei Yan, Xianrang Song, Jinghua Yu, Shanshan Liu, A disposable immunosensor device for point-of-care test of tumor marker based on copper-mediated amplification, Biosensors and Bioelectronics, 2013, 43, 425-431.

11. Shenguang Ge, Weiyan Liu, Lei Ge, Mei Yan, Jixian Yan, Jiadong Huang, Jinghua YuIn Situ Assembly Porous Au-paper Electrode and Functionalization of Magnetic Silica Nanoparticles with HRP via Click Chemistry for Microcystin-LR ImmunoassayBiosensors and Bioelectronics, 49(2013)111–117.

12. Shenguang Ge, Lei Ge, Mei Yan, Xianrang Song, Jinghua Yu* and Jiadong Huang, A Disposable Paper-based Electrochemical Sensor with Addressable Electrode Array for Cancer Screening, Chem. Commun., 2012, 48 (75), 9397 – 9399.

13. Mei Yan#, Shenguang Ge#, Weiqiang Gao, Chengchao Chu, Jinghua Yu, Xianrang Song, Fluorescence Immunosensor Based on p-acid encapsulated Silica Nanoparticles for Tumor Marker Detection, Analyst, 2012, 137 (12), 2834 - 2839.

14. Shenguang Ge, Mei Yan, Juanjuan Lu, Meng Zhang, Feng Yu, Jinghua Yu, Xianrang Song, Shilin Yu, Electrochemical Biosensor Based on Graphene Oxide–Au Nanoclusters Composites for L-Cysteine Analysis. Biosensors and Bioelectronics, 2012, 31, 49-54.

15. Shenguang Ge, Xiuling Jiao and Dairong Chen, Ultrasensitive Electrochemical Immunosensor for CA 15-3 Using Thionine-Nanoporous Gold-Graphene as Platform and Horseradish Peroxidase-Encapsulated Liposome as Signal Amplification, Analyst, 2012, 137, 4440-4447.

16. Shenguang Ge, Feng Yu,Lei Ge, Mei Yan, Jinghua Yu, Dairong Chen, Disposable Electrochemical Immunosensor for Simultaneous Assay the Panel of Breast Cancer Tumor Markers, Analyst, 2012, 137 (20), 4727 - 4733.

17.Shenguang Ge, Juanjuan Lu, Mei Yan, Feng Yu, Jinghua Yu, Xiujin Sun, Fluorescence Resonance Energy Transfer Sensor between Quantum Dot Donors and Neutral Red Acceptors and its Detection of BSA in micelles, Dyes and pigments, 2011, 91, 304-308.

18.Shenguang Ge, Juanjuan Lu, Lei Ge, Mei Yan, Jinghua Yu, Development of a Novel Deltamethrin Sensor Based on Molecularly Imprinted Silica Nanospheres Embedded CdTe Quantum Dots, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2011, 79(5):1704-1709.

19. Shenguang Ge, Congcong Zhang, Yuanna Zhu, Jinghua Yu and Shuangshuang Zhang. BSA activated CdTe quantum dot nanosensor for antimony ion detection. Analyst, 2010, 135, 111– 115.

20. Jinghua Yu, Ping Dai, Shen-guang Ge*, Yuan-na Zhu,Li-na Zhang, Xiao-liang Cheng. Catalytic Dynamic Spectrofluorimetry Determination of Trace Antimony Using New Type Arsenoxylphenylazo Rhodanine. Spectrochimica Acta Part A:  Molecular and Biomolecular Spectroscopy, 2009. 72, 17-21.

 



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